Core concept

Membranes and compartments

Membranes divide the body into compartments with different contents, and control what crosses between them.

Membranes divide your body into compartments with different contents: the fluid inside cells, the fluid around them, and the blood plasma. The plasma membrane keeps potassium high inside a cell and sodium high outside; the capillary wall keeps most plasma proteins in the blood.

Life depends on these differences, and on controlling what crosses between compartments. Water follows solute across membranes, so a change in one compartment's salt concentration moves water in or out of cells. When fluid collects in the wrong compartment, as in swollen ankles, ask which barrier or which force changed.

Where it shows up

Orientation to the body

Cells

Tissues

The brain and spinal cord

The cardiovascular system

Fluid, electrolyte and acid–base balance

Practice it across systems

Mixed questions on membranes and compartments