Core concept
Membranes and compartments
Membranes divide the body into compartments with different contents, and control what crosses between them.
Membranes divide your body into compartments with different contents: the fluid inside cells, the fluid around them, and the blood plasma. The plasma membrane keeps potassium high inside a cell and sodium high outside; the capillary wall keeps most plasma proteins in the blood.
Life depends on these differences, and on controlling what crosses between compartments. Water follows solute across membranes, so a change in one compartment's salt concentration moves water in or out of cells. When fluid collects in the wrong compartment, as in swollen ankles, ask which barrier or which force changed.
Where it shows up
Orientation to the body
Cells
Tissues
The brain and spinal cord
- Meninges, ventricles and cerebrospinal fluid
The cardiovascular system
Fluid, electrolyte and acid–base balance
- Body fluid compartments and water balance